yes
Sometimes you have to shorten the front driveshaft, in my old 96 the front d shaft was so tight I had to use a pry bar to install it, but it fit. Years later I would learn that with a grinder I could remove 1" from the slip yoke on both sides of the front shaft (male and female) and gain 1/2" to make it fit easier.
For the rear driveshaft, since 97-98 expeditions are getting harder to find and the junk yards basically dent every single F150 rear driveshaft with their forklifts, I usually just buy a dented f150 shaft at discount (due to the dent) and have it re tubed at local driveline shop to fit my project.
You will need a conversion U joint at the front shaft where it meets the front diff
You MIGHT need a conversion U joint on the the rear d shaft as well depending on which driveshaft you get.
The only other thing that needs modification, does not just "bolt up" is the 4x4 high and the 4x4 low lights in the dash. I run two wires from the new t case up through the floor to the GEM module. At the GEM module I cut the 4x4 and 4low wires where they go to the dash lights and hook them up directly to the new T case
There are some other tricks to know, like shave all the aluminum ears off the 4406 t case that are not needed, it makes it fit better. Also I modify the transmission cross member to move the 4406 over to the passenger side about 3/8", this helps with the fit, moves the rear d shaft away from the fuel tank shield and also gets rid of rear vibrations some rigs experience from 60-75 mph
There you go 20+ years of conversion experience wrapped up into one thread. The school of hard knocks is a good teacher