Increasing the clearance between the frame, lower control arms, and the ground are key on these trucks. King of So Cal is right on with this...the Truxxx lift + bigger tires is the way to go to accomplish this.
having said that, one area a body lift does help with is getting the running boards/side steps further away from the ground...I cracked one last time I went offroading (at stock height) and hit a rock. Another benefit is it makes it easier to tuck a full size spare (in my case, 265/70/17) further up under the truck in the spare tire area.
Having said that you are limited by the fact that the rear bumper reinforcement that is integrated with the tow hitch is welded to the frame, so no way to move it up. Go with too much body lift, and you have an unsightly gap between the top of the hitch and the bumper cover, and the bumper cover must be trimmed to allow the body to move up past it. The front bumper reinforcement can be moved up but it will take some custom fab, same with the steering shaft needing to be extended.
Due to all of this, I went with a very mild body lift...1". It's not much but it did make a difference. No gap showing in the rear bumper area, and there was no need to move up the front bumper reinforcement, no need for a steering shaft extension, and no need to trim the lower cooling fan shroud. Basically I just bought some 2" body lift blocks and cut them in half, as well as new longer bolts to replace the OEM ones. The pics below show the before and after. Keep in mind that I am also truxxx lifted in the rear and I am running a custom Fox coilover shock setup in the front, which gives both lift and greater suspension travel. This allowed me to remove the front swaybar to allow better front suspension articulation without having any negative affects in body roll or the RSC kicking in:
Before 1" body lift:
After 1" body lift: