When was the last time you replaced plugs and wires? Also get a can of BG 44K and add it to a full tank of gas to clean injectors.
http://www.bgprod.com/products/fuelair.html
This stuff works.Tire pressure,32-35 psi,fuel filter and air filter.Try the basics first.
On my 94 I did a KKM intake and a turbo muffler,NGK plugs and new wires.My around town mileage went from 14 to 16.2 and it runs a lot better.Now this is going to sound stupid but bear with me,have a friend follow you down the 4 lane and listen when you punch the gas,does the exhaust sound like high pressure air? Hissing?
Ford is famous for using quiet but very restrictive mufflers,I can't tell you how many ford trucks I have heard go by hissing like a snake,think of it as trying to breath thru a straw.