When I pulled my original plugs from my '05 4.0, the gaps were ridiculous. Instead of .54 I believe some were around .70, it was no wonder my gas mileage went from 13 to 17 after replacing them. Based on my findings, I'd suggest replacing them at least every 70k.
I also believe the OEs were only platinum on one side, not both. Either way they were far from spec.
I don't know that the 4.0 heads have the same concerns as the 4.6 heads, but I have to respectfully disagree with [MENTION=106710]swshawaii[/MENTION] on the antiseize.
The torque on the plugs isn't much and torque settings are based on resistance. Putting antiseize on the threads reduces torque. So dry 13' lbs is different than lubed 13' lbs. what you'll do, is end up over torquing.
Now, I did use some antiseize, but I only placed it at the end of the threads were they'd be exposed to the elements. To help stop corrosion at that point.