definitely don't run sx's if you do highway driving, they are hard to balance and very loud.
But mainly you'll be getting a massage from these tires.
They come out of balance all the time, they are the worst super swampers for the road next to the boggers.
If you definitely want swampers...SSR's are the most highway friendly. probably radials next.
Oh yeah they got that new tire the TrXus, not as aggresive, but they are actually the most road friendly.
But your best bet if you do a lot of miles are BFG's. they are quality tires.
My friend's dad has some 33 BFG mud terrains on his jeep and they were much much quieter than my 33 TSL radials.
And i'm sure you know about their all-terrain.