Syn Blend vs Full Syn
Synthetics blends are essentially just conventional oils with high grade additives that you find in Full Synthetic oils. While better at keeper an engine clean and prolonging it's ability to suspend contaminants, these additives do not substantially enhance the oils ability to lubricate and protect your engine from extremes in temperature, heavy duty operation or prolong the service intervals.
A high quality Full Synthetic oil such as Mobil 1, changed regularly at intervals of 3500-5000 miles (or even as much as 7500 miles) is the best way to protect and prolong the life of your engine. Use a high quality oil filter as well. Motorcraft is fine but the best on the market currently for filtration is the Purolator Pure One filter that's readily available at most auto parts stores for a reasonable price. Advanced Auto, for instance, around here.
Another advantage to full synthetics is engine operating temperature. Your engine will run marginally cooler with full synthetics so mpg's may increase a bit. I wouldn't count on much measurable improvement however. Your engine's temperature is controlled by a computer and various sensors for the most part in any case. The best 'real world' solution for better mileage is to change your driving habits. Slow down, accelerate slowly and steadily and use cruise control whenever practical.
Hope this helps.