The Dexcool isn't orange. It is pink and should only be installed in GM vehicles. It isn't compatible with etlyne glycol (the green stuff) and can not be mixed. I'm not sure if there are other issues as well that would need to be addressed.
I believe you are referring to the orange "extended life" antifreeze. It is compatible with the standard green antifreeze however you don't get the extended life properties unless you go through the proper flushing procedures with the proper flush solution. If you go throug the proper procedure then the antifreeze is supposed to be good for 5 years, 100K miles. I did use Prestone's extended life antifreeze a couple of years ago when I did my flush. A couple months later I had to have my water pump replaced at Ford and I told them that I had the extended life antifreeze in my Explorer. If they didn't carry it, then I would bring in a couple new bottles. They assured me it wouldn't be any problem. When i got it back, my reservoire was still full of the orange coolant so I figured they used the right fluid. The radiator was too hot to open. About a week later I looked in my radiator and sure enough it was filled with the standard green antifreeze so I lost the extended life properties.
A couple months later I took it back to the same dealer since it was running hot. By then my green fluid mixed with my orange fluid and turned brown. The dealer called me back telling me I had to have a complete flush done since I mixed the two fluids together. After trying to explain to the Service Advisor that they were the ones that mixed them two months earlier and besides that the two fluids were compatible according to my Prestone bottle of which I would be more than happy to take it up to him and show him. He refused to touch my Explorer unless I authorized him to do the coolant flush. He said his Technician told him the two fluids were separating and that was causing my overheating problem. I told him to go ahead. I went home that night and mixed a 50/50 bottle of the orange and green coolants together. The next day I took my empty Prestone bottle and my mixed bottle of coolant up to the dealer. When I got up there he told me the problem turned out to be a stuck thermostat but insisted that I needed his $135 power flush. After arguing with the Service Manager and showing him my bottles he asked the Technician what fixed the problem. When the Technician told him that a new thermostat fixed it but he had a letter from Ford advising him that under no circumstances could the green antifreeze be mixed with GM's Dexcool. I was quick to point out that there wasn't any Dexcool in my Explorer so they agreed to remove the flush charge from my bill.
So the short answer is no I haven't used Dexcool, but I have used the orange antifreeze but only for two months so I can't say if it lived up to its promises.