Cory already hates everything I've done so far (D30, leaf springs, fiberglass), so I'll go ahead and argue.
Here's some points that I've considered:
1. I've already got the 8.8
2. Already have the 4.56 grears, detroit locker, disc brakes
3. It fits within my body and is legal, I'd have to cut down a D60 or 14 bolt.
4. I already paid for expensive 17x10 5on 4.5 rims. Wife said no more wheels!
5. Strength is not an issue with me. I've very confident in the 8.8, however, I do like the idea of IF I ever break an axle, I can just drive home.
6. If I step up to a V8, then I'll worry about strengh a little more.
If I were to start with a bone stock X, then Dana 60s would be the better choice.