I've seen both drive shafts taken out of 4wd trucks and towed (either broken down towing it to a shop or home, or some other reason), I haven't seen ANY problems with taking both drive shafts out, even a slightly newer truck (2004), not sure if what trucks/cars you can remove both shafts from, but if you have the tools handy, you can make it happen, I just wouldn't go above 45mph, the fastest I've allowed them to go is 25mph-35mph for about 1-2 miles at stop and go traffic. Even though both drive shafts are out, still need to be cautious.