This issue just popped up on my 2020 Limited yesterday. I was driving down the road and I adjusted the temperature. As soon as I touched the temp toggle the audio stopped. Now it just says "Audio off" no matter how many times you hit the physical or touch button. I first tried turning off the vehicle and turning it back on. Nothing. I then went nuclear immediately and did a factory reset. This resulted in a permanent black screen. I was luckily able to do the POWER + SEEK RIGHT for 10 seconds trick to get it to come back online, but still "AUDIO OFF".
I guess off to the dealer I go...